Focal123I-FP-CIT SPECT Abnormality in Midbrain Vascular Parkinsonism

Focal 123I-FP-CIT SPECT Abnormality in Midbrain Vascular Parkinsonism

Cerebrovascular diseases are considered among possible causes of acute/subacute parkinsonism, representing up to 22% of secondary movement disorders. In cases of suspected vascular parkinsonism (VP), dopamine transporter SPECT has been highly recommended to exclude nigrostriatal dopaminergic degeneration. We report the case of a hemiparkinsonism related to a left midbrain infarct with focal lat...

[123I]FP-CIT SPECT in atypical degenerative parkinsonism

Parkinson’s disease (PD) is the second most common neurodegenerative disorder [1], yet early accurate diagnosis remains challenging. The estimated prevalence of PD is 0.5–1% in those aged 65–69 years and 1–3% in those aged ≥80 years [1]. Although the clinical diagnosis of PD may be straightforward in cases with a classic presentation [2], accurate distinction between PD and atypical degenerativ...

I]FP-CIT SPECT images

Aim The purpose of the current paper is to present a computational solution to accurately quantify a specific to a non-specific uptake ratio in [ 123 I]FP-CIT single photon emission computed tomography (SPECT) images and simultaneously measure the spatial dimensions of the basal ganglia, commonly known as basal nuclei. A statistical analysis based on a reference dataset selected by the user is ...

Diagnostic accuracy of 123 I-FP-CIT SPECT in diagnosing drug-induced parkinsonism: a prospective study.

INTRODUCTION Drug-induced parkinsonism is a major type of parkinsonism in our setting. Symptoms usually disappear after discontinuation of the drug. However, they may persist in patients with a variant known as subclinical drug-exacerbated parkinsonism; early identification of this entity has important prognostic and therapeutic implications. The most widely used complementary test in this diag...

Diagnostic accuracy of I-FP-CIT SPECT in diagnosing drug-induced parkinsonism: A prospective study